Phenomena vs Drug Use

The use and endorsement of drugs and alcohol at RSE by JZ Knight
Kensho
Posts: 693
Joined: Mon Mar 16, 2009 11:52 pm

Phenomena vs Drug Use

Unread post by Kensho » Fri Aug 28, 2009 3:24 pm

Datura
http://en.wikipedia.org/wiki/Datura_stramonium#Effects

from above link:
The physiological effects are reported to be cycloplegia and mydriasis (extreme dilation of the pupil), flushed, warm and dry skin, dry mouth, urinary retention and ileus (slowing or stopping of intestinal movement), tachycardia, hypertension or hypotension, and choreoathetosis/jerky movements.

(urinary retention: could this be a possible reason that someone we know didn't need to leave the arena to pee?)

Cocaine
http://www.nida.nih.gov/Infofacts/cocaine.html

from above link
...cocaine constricts blood vessels, dilates pupils, and increases body temperature, heart rate, and blood pressure.

Added Danger: Cocaethylene
Polydrug use?use of more than one drug?is common among substance abusers. When people consume two or more psychoactive drugs together, such as cocaine and alcohol, they compound the danger each drug poses and unknowingly perform a complex chemical experiment within their bodies. Researchers have found that the human liver combines cocaine and alcohol to produce a third substance, cocaethylene, that intensifies cocaine?s euphoric effects.
Cocaine and Alcohol Interactions in Humans: Neuroendocrine Effects and Cocaethylene Metabolism1

http://jpet.aspetjournals.org/cgi/conte ... /283/1/164

from above link:
The combination of alcohol and cocaine produced greater increases in HR (heart rate), rate-pressure product and pleasurable-related subjective effects (euphoria, well-being) compared with the effects of cocaine. The drug combination reduced the alcohol-induced sedation, but feelings of drunkenness were not significantly counteracted.

The augmented subjective euphoria may explain why the drug combination is more likely to be abused than is cocaine or alcohol alone.

ex
Posts: 857
Joined: Sun Jan 06, 2008 9:18 am

Unread post by ex » Sat Aug 29, 2009 3:06 pm

yes thank you for this brilliant research. elevated pupills were allways a sign of druguse to me. since jzr is very loose in promoting 'littel helpers'[like wine prosac seewater..]the conclusens are obviews.

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