Colloidal Silver: Risk Without Benefit

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David McCarthy
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Colloidal Silver: Risk Without Benefit

Unread post by David McCarthy »

Debunking Colloidal Silver...
Ouch..do we really need go there?
chuckle...
I recently received an Email regarding an article titled Colloidal Silver: Risk Without Benefit.
Copied from an interesting website called Quackwatch..
http://www.quackwatch.org/index.html
Title: Colloidal Silver: Risk Without Benefit
To view the entire article with hyperlinks, click on the link below or cut and paste it into a web browser:
http://www.quackwatch.org/01QuackeryRel ... verad.html
This one is for Kensho "and others" who have extensive experience in health care.
I have a large bottle of Colloidal Silver on top our kitchen cupboard that I often stare up to in great reverence...... but after reading this article my bubble has been popped..it may very well may be heading for the trash can.
I wonder if others on EMF have a evidence to the contrary that Colloidal Silver is at best a placebo, or at worst, a poison.

Anyone?

Thank you M.

David.

______________________________________________________

Colloidal silver is a suspension of submicroscopic metallic
silver particles in a colloidal base. Long-term use of silver
preparations can lead to argyria, a condition in which silver
salts deposit in the skin, eyes, and internal organs, and the
skin turns ashen-gray. Many cases of argyria occurred during the
pre-antibiotic era when silver was a common ingredient in nosedrops.
When the cause became apparent, doctors stopped recommending their
use, and reputable manufacturers stopped producing them. The official
drug guidebooks (United States Pharmacopeia and National Formulary)
have not listed colloidal silver products since 1975.

Dubious Ads

In recent years, silver-containing products have been marketed
with unsubstantiated claims that they are effective against AIDS,
cancer, infectious diseases, parasites, chronic fatigue, acne,
warts, hemorrhoids, enlarged prostate, and many other diseases
and conditions. Some marketers claim that colloidal silver is
effective against hundreds of diseases.

During 1997 and 1998, Changes International, a Florida-based
multilevel company, stated:

Our colloidal silver contains 99.99% pure silver particles
suspended indefinitely in demineralized water that kills bacteria
and viruses. It can be applied topically and/or absorbed into
the blood stream sub-lingually (under the tongue), thereby avoiding
the negative effects of traditional antibiotics that kill good
bacteria in the lower digestive tract.
An all natural antibiotic alternative in the purest form available.
The presence of colloidal silver near a virus, fungi, bacterium
or any other single celled pathogen disables its oxygen-metabolism
enzyme, its chemical lung, so to say. The pathogens suffocates
and dies, and is cleared out of the body by the immune, lymphatic
and elimination systems.
Unlike pharmaceutical antibiotics which destroy beneficial
enzymes, colloidal silver leaves these beneficial enzymes intact.
Thus colloidal silver is absolutely safe for humans, reptiles,
plants and all multi-celled living matter.
It is impossible for single-celled germs to mutate into silver-resistant
forms, as happens with conventional antibiotics. Also, colloidal
silver cannot interact or interfere with other medicines being
taken. Colloidal silver is truly a safe, natural remedy for many
of mankind's ills. Colloidal silver can be taken indefinitely
because the body does not develop a tolerance to it [1].

Seasilver International,
a California-based multilevel company, had claimed that American are
suffering from "silver deficiency." Although silver
is not an essential nutrient, product information posted on the
company's Web site several years ago stated:

The depletion of minerals in our soil has left us deficient
of silver, one of our most essential trace minerals, causing
a drastic increase in immune system disorders in our society
in the last decade. Research has taught us that all disease is
allowed to manifest itself because of a weakened immune system.
In over 20 years of worldwide research on Colloidal Silver, numerous
interviews with government agencies, health care practitioners
and their patients, no other nutrient, herb or drug (prescription
or over-the-counter) is as safe and effective against all known
forms of unfriendly virus, bacteria, and fungus. Additionally,
while it is generally known that most antibiotics kill only perhaps
6 or 7 different disease organisms, reports have shown that Colloidal
Silver has been used successfully in the treatment of over 650
diseases! Furthermore, strains of disease organisms fail to develop
in the presence of Colloidal Silver. Colloidal Silver's greatest
attribute is its unique ability to function as a superior second
immune system in the body! [2]

The ad below is from the July 1996 issue of Alternative
Medicine Digest.

Critical Studies and Case Reports

In 1995, an herbal distributor named Leslie Taylor tested nine
commonly marketed colloidal silver products available at health-food
stores and concluded:

Two of the products were contaminated with microorganisms.
The amount of silver suspended in solution varied from product
to product and would gradually decrease over time.
Only five products actually showed antibacterial activity
in a laboratory test. To perform the test, she prepared a culture
plate with Staphylococcus aureas bacteria, which can cause infections
in humans. She then placed a drop from each product on the plate
and used disks of two common antibiotics as controls. After eight
hours of incubation, she found that bacterial growth had been
inhibited around the antibiotics and four of the products.

Of course, the fact that a product inhibits bacteria in a laboratory
culture doesn't mean it is effective (or safe) in the human body.
In fact, products that kill bacteria in the laboratory would be
more likely to cause argyria because they contain more silver
ions that are free to deposit in the user's skin.

FDA laboratory studies have found that the amount of silver
in some product samples has varied from 15.2% to 124% of the amount
listed on the product labels. The amount of silver required to
produce argyria is unknown. However, the FDA has concluded that
the risk of using silver products exceeds any unsubstantiated
benefit [3]. So far, eleven cases of argyria related to silver products
have been reported:

A 56-year-old man who had sold and used colloidal silver
for three years, developed blue/gray discoloration of his fingernails
accompanied by a very high blood level of silver [4].
A married couple who had three years of daily consumption
of a drink prepared by administering an electrolytic charge to
a bowl of water that contained a silver bar [5].
Another couple had been taking a silver-containing "dietary
supplement" prescribed by a naturopath [5].
A mentally ill man who had been drinking silver-containing
herbal tea for about 10 months [5].
Stan Jones, Montana's Libertarian Party candidate for the
U.S. Senate, who reportedly started taking colloidal silver in
1999 for fear that Y2K disruptions might lead to a shortage of
antibiotics. He made his own concoction by electrically two silver
wires in a glass of water [6].
Two men, ages 63 and 76, developed argyria after a year of
product use inspired by Internet claims [7].
A 16-year-old boy developed blue-gray pigmentation of his entire body after ingesting a silver-containing dietary supplement for a year. The product, packaged so that it was identical to bottled water. was touted as a preventive for everyday infections [8].


A 58-year-old man who treated a presumed kidney infection with a home-brewed colloidal solution 12 times a day for 4 days developed argyria about 4 weeks later [9].
A 38-year-old man developed argyria after ingesting approximately 16 ounces of 450 ppm colloidal silver three times a day for 10 months to treat his arthritis and other conditions. He made the solution with a simple battery-operated chamber that leached silver from pure silver wire. He had obtained the plans from information on the Internet [10]. The photograph to the right shows how his skin color compares to that of normal skin.

 



Enforcement Actions

Between October 1993 and September 1994, the FDA issued warning
letters to five colloidal silver marketers::

Higher Education Library Publications (H.E.L.P.), of Springfield,
Utah, was ordered to stop claiming that its colloidal silver
product was effective as a natural antibiotic and might be effective
against cancer, genito-urinary diseases, tuberculosis, and AIDS.
Nutrition, Inc., of Arvada, Colorado, was ordered to stop
stating or implying that its Silvicidal, when administered
orally or intravenously, was nontoxic, FDA-approved, and was
a broad-spectrum antibiotic that killed bacteria and all virus
and fungal infections. In addition, it was falsely claimed to
be effective against a long list of specific diseases.
Reseau International of Cincinnati, Ohio was ordered to stop
claiming that its colloidal silver product was a "natural
antibiotic and anti-inflammatory immune system stimulant"
and that it was effective against cancer, staph, strep, influenza,
general body infections, inflammation, impaired immune system,
fungus toxicity, tonsillitis, Meniere's symptoms, whooping cough,
shingles, syphilis, cholera, and malaria. The labeling also stated
that colloidal silver could cause major growth stimulation of
human tissues and can regenerate
Silverado Inc., of Bountiful, Utah, was warned to stop making
false claims that its colloidal silver product was effective
as an antibiotic, anti-inflammatory, anti-viral, and anti-fungal
agent and that it could stimulate the immune system.
Unic, of Carmichael, California, was ordered to stop claiming
that its colloidal silver product was effective against many
diseases and could heal burn-damaged tissue without scarring.

In October 1996, the FDA proposed to ban the use of colloidal
silver or silver salts in over-the-counter products [11]. A Final
Rule banning such use was issued on August 17, 1999 and became
effective September 16th. The rule applies to any nonprescription
colloidal silver or silver salt product claimed to be effective
in preventing or treating any disease [12]. Silver products can
still be sold as "dietary supplements" provided that
no health claims are made for them. During 2000, the
FDA issued warnings to more than 20 companies whose Web sites
were making illegal therapeutic claims for colloidal silver products.

In 2000, the Federal Court of Australia banned Vital Earth
Company Pty Limited and its director Darryl John Jones from falsely
representing that the colloidal silver produced by their "Vital
Silver 3000 Zapper," "Vital Silver 2000 Automatic"
and "Vital Silver 2000":

Can kill all disease-causing bacteria, fungi and virus within
six minutes of contact
Has no harmful side effects; that colloidal silver could
be used as an antibiotic for all the acquired diseases of active
AIDS
Is effective with more than 650 different pathogenic bacteria
and virus types
Has been used successfully against diseases including AIDS,
cholera, diabetes, leprosy, leukemia, lupus, skin cancer, syphilis
and whooping cough.

The company was also ordered to pay AUS$9000 in costs and to
provide refunds [13].

In 2001, the FTC obtained consent agreements with two companies:

Robert C. Spencer and Lisa M. Spencer, doing business as
Aaron Company (Palm Bay, Florida). Colloidal silver has been
medically proven to kill over 650 disease-causing organisms in
the body and is effective in curing diseases ranging from cancer
and multiple sclerosis to HIV/AIDS [14].
ForMor, Inc., doing business as ForMor International, and
its president, Stan Gross (Birmingham, Alabama) agreed not to
make unsubstantiated claims that colloidal silver is effective
in treating over 650 infectious diseases, has no adverse side
effects, and is effective against arthritis, blood poisoning,
cancer, cholera, diphtheria, diabetes, dysentery, gonorrhea,
herpes, influenza, leprosy, lupus, malaria, meningitis, rheumatism,
shingles, staph infections, strep infections, syphilis, tuberculosis,
whooping cough, and yeast infections [14].

In 2002, the FTC obtained a consent agreement with Kris Pletschke,
doing business as Raw Health,
agreed to stop making unsubstantiated claims that its colloidal
silver product could treat or cure 650 different diseases; eliminate
all pathogens in the human body in six minutes or less; and is
medically proven to kill every destructive bacterial, viral, and
fungal organism in the body, including anthrax, Ebola, Hanta,
and flesh-eating bacteria [15].

In 2002, the Australian Therapeutic Goods Administration amended
its rules so that water-treatment products containing substances
like colloidal silver for which therapeutic claims are made must
meet the requirements of medicines included in the Australian
Register of Therapeutic Goods. This means that such products can
no longer be legally marketed without proof that they are safe
and effective for their intended purpose. The amendment was based
on clnclusions that:

There is little evidence to support therapeutic claims made
for colloidal silver products;
The risk to consumers of silver toxicity outweighs the value
of trying an unsubstantiated treatment, and bacterial resistance
to silver can occur
Efforts should be made to curb the illegal availability of
colloidal silver products, which is a significant public health
issue
But he has nothing on at all, cried at last the whole people....
Kensho
Posts: 693
Joined: Mon Mar 16, 2009 11:52 pm

Buyer beware...

Unread post by Kensho »

Hello David and others,

Ah yes, colloidal silver is another one of those substances that is still being investigated on many fronts with respect to efficacy and risk-benefit. Colloidal silver is a relatively big seller-but so are alcohol and chocolate (each of which have been reported to have beneficial influences on the immune system and general health).
David, as you seem to suffer from periodic deficiencies of the "dark bar" anyway, I'd stick with the chocolate in your case ;-) .

It seems that the number of reported and documented adverse reactions or toxic side effects of the supplemental or home-made forms are minimal when compared to the number of people who use a form of this substance. That is not to say that it is safe for use, but just one more thing to consider in evaluation whether one should use it.
The question remains, is colloidal silver effective in safely controlling or treating infection beyond a placebo effect?

As a nutritionist, I find it best to rely upon scientifically proven, unbiased evidence-based data with respect to efficacy and risk of any substance or treatment, rather than on mainstream, heavily promoted or trendy theories, which in large part may only be based on hypotheses and unproven scientifically.

As an example, if we briefly look at the controversy regarding a common supplement such as calcium, it might be better to wait for similar amounts of evidence with respect to something like colloidal silver, especially for long-term use:

Calcium supplementation has been promoted to be effective in the treatment or prevention of osteoporosis (its main supplemental use), but surely with the levels of calcium supplementation that have taken place in North America over the last three decades, osteoporosis should be a thing of the past on this continent.

Yet North Americans continue to have a very high incidence of Osteoporotic disease per capita, despite supplementation. Compare that statistical information to that with respect to populations in the third world that do not have this disease despite low levels of calcium in their diet and little supplementation of calcium.

North Americans also have a very high per capita incidence of calcium deposition diseases like kidney and gall stones, coronary and small artery disease, electrolyte (mineral) related digestive, endocrine gland and neurological dysfunction; where those in the third world do not.
It has been hypothesized, (yet unproven as of yet) that high calcium ingestion may be related to these disease states. Casual analysis of the apparent relationship in populations with respect to dietary and supplemental calcium seems to support that hypothesis.

All hypotheses aside there are some proven dangers with respect to use of some calcium supplements. Evidence does exist that there has been lead/heavy metal contamination of calcium supplements that are sourced from bone meal (cattle bones) and dolomite. The expectation is that similar contaminants might be found in other sources of calcium extraction, like coral (coral calcium) and sea water.

Alert! Coral Calcium Supplements Scam
http://www.healthcastle.com/coralcalcium-scam.shtml

Dolomite calcium toxicity:
http://www.drugs.com/npp/dolomite.html

Dolomite mined from a location near a lead mine was found to contain up to 2,700 ppm (after addition to animal feed), a level that would have induced lead toxicity in the cattle that ingested it; milk and meat products from these animals would have been unsafe for human consumption. (Bone meal extracted from these animals for supplement use would also presumably be toxic.)

Of similar concern has been the detection of elevated levels of heavy metals in dolomite preparations intended for human consumption. One product, for example, that was used as a mineral supplement was contaminated with aluminum (187 ppm), lead (35 ppm), nickel (13 ppm), arsenic (24 ppm) and mercury (12 ppm), among other trace elements.

Contaminated dolomite products have been reported to precipitate psychomotor seizures in otherwise controlled epileptics.
The implications of long-term use of such a supplement could prove to be devastating to the health of those that use it on other fronts as well.

In the final analysis, based on the evidence available thus far, the efficacy of generalized calcium supplementation in the treatment or prevention of osteoporosis quite simply does not exist. However there is growing evidence that such supplementation may actually be a contributing factor to other diseases.

So with such evidence available, why does calcium supplementation continue to be heavily promoted? Simple...it is a multi-billion dollar industry with respect to both the provision/sale of the substance as well as the treatments required for the possible detrimental side-effects of its use. Always follow the money!

So much for Judith's promotion of calcium supplementation...

NOTE: The unproven promotion and use of substances holds true with respect to many chemotherapeutics and/or drug therapies as well.


Back to the question of Colloidal silver:

Similar concerns remain with respect to evidence based studies on efficacy, toxicology studies of the substance itself as well as the potential presence of other contaminants within supplemental forms, and are worth considering before using it.
The two best sources that I have found for accessing EVIDENCE BASED information on treatments, drugs and supplements are:

1. The Cochrane Collaboration
http://www.cochrane.org/

It is a shame that a search of this data base for colloidal silver has no data, for it I have found that it is by far the most comprehensive and reliable; based on the methods of data selection and collection.


2. The Pubmed data base:
U.S. National Library of Medicine
National Institutes of Health

Search results for colloidal silver came up with over 700 peer reviewed research papers:
http://www.ncbi.nlm.nih.gov/sites/entre ... ated_query

Here are two papers that seem to best summarize the findings of other non-biased research studies that have been conducted thus far.
-Silver in health care: antimicrobial effects and safety in use.
Imperial College Faculty of Medicine, Charing Cross Hospital, London, UK. a.lansdown@imperial.ac.uk

http://www.ncbi.nlm.nih.gov/pubmed/1676 ... stem2.PEnt rez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=9


-Silver products for medical indications: risk-benefit assessment.
Fung MC, Bowen DL.Center of Drug Evaluation and Research, Food and Drug Administration,
Rockville, Maryland, USA.

http://www.ncbi.nlm.nih.gov/pubmed/8632 ... tem2.PEntr ez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=15




It would seem that in cases of laboratory confirmed diagnosis of specific infection, the tested and proven treatments are often the best and safest way to go (Cochrane Collaboration).

Yet if one is motivated to try a supplement that is reported to have any immediate or dramatic effect, before investing in a large supply of the stuff, it is probably best to conduct a short trial (5-10 days is usual), preferably under the supervision of a health care practitioner who has knowledge of the substance; then to make an assessment as to whether or not there are perceived benefit and/or unwanted side effects.
Note that short term use and long term use of many substances often have different effects that may be beneficial or detrimental.

It is also prudent before conducting a personal trial, to inquire with a pharmacist with respect to supplement-drug and supplement-disease interactions. These interactions are also sometimes listed in pharmaceutical compendiums and in the Pubmed data base.

Hope this helps.

Much love, Kensho
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David McCarthy
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Unread post by David McCarthy »

Thank you Kensho,
I so appreciate your genuine TLC at the core of all your posts ,.
Thank you.... :
there is a new MLM product circulating Yelm called "Silver Sol"
claimed to be wonderful "business opportunity" due to its wonderouse heath benefits..... :-?

Here we are 2010...Happy New Year everyone....
especially our fabulous EMF moderator team.....

David.
But he has nothing on at all, cried at last the whole people....
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